Evidence supporting the use of: Amylase (mixed amylase)
For the body system: Pancreatic Tail

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Amylase is an enzyme responsible for the breakdown of starches into simple sugars, a crucial step in the digestive process. In humans, amylase is produced primarily by the pancreas and the salivary glands. The reference to the "pancreatic tail body system" pertains to the pancreas, specifically the tail region, which is one site of amylase secretion. Supplementation with mixed amylase (from microbial, fungal, or porcine sources) is scientifically validated in the management of exocrine pancreatic insufficiency (EPI), a condition in which the pancreas does not produce enough digestive enzymes, including amylase. Clinical guidelines and multiple studies support the use of pancreatic enzyme replacement therapy (PERT), which includes amylase, to improve digestion, nutrient absorption, and quality of life in patients with EPI due to chronic pancreatitis, cystic fibrosis, or after pancreatic surgery (Sikkens et al., 2017). While amylase alone is not typically used in isolation for pancreatic support, it is an essential component of standard enzyme replacement formulations. There is less evidence for its use in healthy individuals or in supporting the pancreas outside of deficiency states, but its use in documented pancreatic enzyme insufficiency is well-supported by scientific research.

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