Evidence supporting the use of: Charantin
For the body system: Pancreatic Tail

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Charantin is a bioactive compound found primarily in the bitter melon plant (Momordica charantia). Its primary scientific relevance lies in its hypoglycemic (blood sugar-lowering) effects. Several animal studies and a limited number of small-scale human trials have demonstrated that charantin possesses insulin-mimetic properties, which may enhance glucose uptake and utilization. The pancreas, specifically the beta cells (primarily located in the tail region of the pancreas), plays a critical role in insulin production and secretion.

Charantin’s purported effect is to support pancreatic function by stimulating insulin secretion or mimicking its action, thereby lowering blood glucose levels. This has led to its investigation as a herbal adjunct in the management of diabetes mellitus, a disease closely associated with pancreatic beta cell dysfunction. However, while preclinical data is promising, robust, large-scale human clinical trials are lacking, and the precise mechanism of action remains to be fully elucidated. The evidence thus far is sufficient to justify its inclusion in scientific discussions but not conclusive for therapeutic recommendations.

In summary, the use of charantin to support the pancreatic system, particularly the insulin-producing function of the pancreatic tail, is supported by moderate scientific evidence, mostly from in vitro and animal studies, with some small human trials. Further research is necessary to fully validate its efficacy and safety in humans.

More about Charantin
More about Pancreatic Tail

Other body systems supported by Charantin

Blood
Pancreas Head
Pancreatic Tail

Products containing Charantin

We currently have no products on Vitabase that contain this ingredient.