Evidence supporting the use of: Charantin
For the body system: Pancreatic Tail
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Charantin is a bioactive compound found primarily in the bitter melon plant (Momordica charantia). Its primary scientific relevance lies in its hypoglycemic (blood sugar-lowering) effects. Several animal studies and a limited number of small-scale human trials have demonstrated that charantin possesses insulin-mimetic properties, which may enhance glucose uptake and utilization. The pancreas, specifically the beta cells (primarily located in the tail region of the pancreas), plays a critical role in insulin production and secretion.
Charantin’s purported effect is to support pancreatic function by stimulating insulin secretion or mimicking its action, thereby lowering blood glucose levels. This has led to its investigation as a herbal adjunct in the management of diabetes mellitus, a disease closely associated with pancreatic beta cell dysfunction. However, while preclinical data is promising, robust, large-scale human clinical trials are lacking, and the precise mechanism of action remains to be fully elucidated. The evidence thus far is sufficient to justify its inclusion in scientific discussions but not conclusive for therapeutic recommendations.
In summary, the use of charantin to support the pancreatic system, particularly the insulin-producing function of the pancreatic tail, is supported by moderate scientific evidence, mostly from in vitro and animal studies, with some small human trials. Further research is necessary to fully validate its efficacy and safety in humans.
Other ingredients that support Pancreatic Tail
bitter melongurmar
lipase
microbial enzymes (proprietary)
starch
water
enicostemma littorale
pterocarpus marsupium
sodium salt
nopal
Charantin