Evidence supporting the use of: Gymnemagenin
For the body system: Pancreatic Tail

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Gymnemagenin is a bioactive saponin aglycone found in the plant Gymnema sylvestre, which has a long history of use in traditional Ayurvedic medicine for managing diabetes. Modern scientific studies have investigated the effects of Gymnema sylvestre extracts (which contain gymnemagenin among other compounds) on pancreatic function, particularly regarding blood glucose regulation. Research suggests that gymnemagenin may contribute to the regeneration of pancreatic beta cells, which are located primarily in the tail and body of the pancreas and are responsible for insulin secretion. Several animal studies have demonstrated a restoration of islet architecture and improved insulin levels following administration of Gymnema extracts. However, it is important to note that most studies use whole plant extracts rather than isolated gymnemagenin, so attributing effects solely to gymnemagenin is challenging. Human clinical data is limited but promising, showing improved glycemic control in diabetic patients using Gymnema supplements. Thus, while tradition supports the use of Gymnema for pancreatic health, there is moderate scientific evidence—primarily preclinical and some clinical—for the beneficial effects of its components, including gymnemagenin, on the pancreatic tail and beta cell function.

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Other body systems supported by Gymnemagenin

Gastrointestinal Tract
Pancreas Head
Pancreatic Tail
Small Intestines

Products containing Gymnemagenin

We currently have no products on Vitabase that contain this ingredient.