Evidence supporting the use of: Abrus
For the health condition: Parasites (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Abrus, most commonly referring to Abrus precatorius (rosary pea), has been used in various traditional medicine systems, including Ayurveda and folk medicine in Africa and Asia, for the treatment of parasitic infections. Ethnomedicinal reports indicate that decoctions or powders made from the leaves, seeds, or roots have been employed for ailments such as intestinal worms or other internal parasites. The rationale in folk medicine is likely attributed to the plant’s known toxicity and potent bioactive compounds, such as abrin (a highly toxic protein), flavonoids, and alkaloids, which might have anthelmintic (anti-parasitic) properties.

However, scientific validation for these uses is limited. Some in vitro and animal studies suggest extracts of Abrus can have antiparasitic or anthelmintic activity, but these studies are few, often preliminary, and do not provide sufficient evidence for safety or efficacy in humans. Furthermore, the seeds are extremely toxic, and improper use can result in fatal poisoning.

In summary, the use of Abrus for general parasites is supported primarily by traditional use rather than robust scientific evidence. Caution is advised due to the serious risks associated with its toxicity, and it should not be used without proper processing and expert supervision.

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