Evidence supporting the use of: Abuta
For the health condition: Parasites (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Abuta (commonly referring to Cissampelos pareira or related species in the Menispermaceae family) has a history of traditional use in South American and Amazonian ethnomedicine for various ailments, including as an antiparasitic remedy. Indigenous groups and traditional healers have used preparations of Abuta roots or stems to treat symptoms associated with parasitic infections, such as gastrointestinal disturbances, although the specific parasites targeted are often not clearly defined in ethnobotanical records.

Scientific validation for its antiparasitic properties is limited. Some in vitro studies have examined extracts of Cissampelos pareira and related species for activity against protozoa and helminths, with mixed and generally modest results. However, robust clinical evidence in humans is lacking, and there are few, if any, controlled animal studies directly demonstrating efficacy against common human parasites. The plant contains a variety of alkaloids, some of which have demonstrated biological activity, but their relevance to antiparasitic effects remains unclear.

In summary, while Abuta is traditionally used for treating parasite-related conditions in certain cultures, there is insufficient modern scientific evidence to strongly support its efficacy for this purpose. The evidence is primarily ethnobotanical and anecdotal, rather than experimentally validated.

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