Evidence supporting the use of: Black walnut
For the health condition: Parasites (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Black walnut (Juglans nigra) hulls have a long history of use in traditional herbal medicine for the treatment of intestinal parasites. Herbalists and folk practitioners, particularly in North America and Europe, have used black walnut for centuries as a remedy for worms and other gastrointestinal parasites. The primary compound believed to be responsible for these purported effects is juglone, a naphthoquinone with demonstrated antimicrobial and antifungal properties in laboratory settings. However, direct scientific studies on the efficacy of black walnut hulls against human intestinal parasites are limited. Most available evidence supporting its antiparasitic effects comes from in vitro studies or animal models, rather than well-controlled human clinical trials.

Despite the lack of robust clinical evidence, black walnut continues to be included in many commercial “parasite cleanse” supplements. The traditional use is further bolstered by anecdotal reports, but scientific validation remains weak. Therefore, while the use of black walnut for parasites is primarily justified by tradition, and there is some laboratory evidence of antimicrobial activity, the clinical support is minimal. It is important for users to be aware that safety data is also limited, and black walnut can be toxic in high doses or with prolonged use.

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