Evidence supporting the use of: Calotropis gigantea
For the health condition: Parasites (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Calotropis gigantea, commonly known as crown flower or "arka," has a long history of use in traditional medicine systems such as Ayurveda and folk remedies across Asia and Africa for treating various parasitic infections. Traditional healers have employed different parts of the plant—especially the latex, leaves, and root bark—as anthelmintic agents to expel or manage intestinal worms and other parasites. The latex is particularly noted for its purported vermifuge properties in ethnomedical literature. However, the scientific evidence supporting these uses is limited. Some preliminary in vitro and animal studies indicate that extracts from Calotropis gigantea may possess some antiparasitic activities, particularly against helminths (parasitic worms), likely due to bioactive compounds such as cardenolides and proteolytic enzymes. These studies, however, are neither extensive nor conclusive, and comprehensive clinical trials in humans are lacking. As a result, while the traditional use is well-documented and there is some low-level scientific support, the overall quality and quantity of evidence remain modest. Caution is advised, as parts of the plant are known to be toxic, and improper use can lead to adverse effects.

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