Evidence supporting the use of: Ipomoea jalapa
For the health condition: Parasites (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ipomoea jalapa, commonly known as jalap, has a long history of traditional use as a purgative and vermifuge (expeller of intestinal worms). The tuberous roots of this plant were used by indigenous peoples of Mexico and Central America and later adopted into European herbal medicine from the 16th century onward. The primary traditional application was as a potent purgative to cleanse the bowels, which, by promoting rapid evacuation, was believed to help expel intestinal parasites ("worms"). Early pharmacopoeias, such as the British and United States Pharmacopoeia, included jalap as a standard anthelmintic (anti-parasitic) and cathartic.

The active compounds in Ipomoea jalapa are resin glycosides (jalapins), which are known for their strong laxative effects. However, there is little to no modern clinical evidence specifically validating its efficacy or safety for treating parasitic infections in humans. Most of its use for this indication remains rooted in traditional and historical medical practice rather than contemporary scientific validation. Adverse effects, including severe gastrointestinal distress, have limited its use in modern medicine. As such, while there is a clear traditional precedent for using jalap against intestinal parasites, the evidence supporting its effectiveness is largely historical and not substantiated by rigorous scientific studies.

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