Evidence supporting the use of: Stemona
For the health condition: Parasites (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Stemona (particularly the roots of Stemona sessilifolia, Stemona japonica, and Stemona tuberosa) has been used in traditional Chinese medicine for centuries, primarily as an antitussive and anthelmintic (anti-parasitic) agent. Historical texts, such as the Chinese Pharmacopoeia, describe its use for expelling parasites like lice and intestinal worms. The use against parasites is mostly topical (e.g., treating lice and scabies), but some traditional formulations also recommend it for internal parasitic infections.

Scientific studies on Stemona's anti-parasitic activity are limited. Some in vitro and animal studies suggest the presence of alkaloids (notably stemonine and tuberostemonine) with activity against head lice and certain nematodes, but robust clinical trials in humans are lacking. Thus, the evidence largely remains empirical and based on traditional use, with only preliminary pharmacological support. No major international health authority currently recognizes Stemona as a standard treatment for parasitic infections.

In summary, Stemona’s use for parasites is primarily justified by traditional practice, with some supportive but not definitive preclinical evidence. More rigorous scientific studies are needed to validate its efficacy and safety for this purpose.

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