Evidence supporting the use of: Blepharis
For the health condition: Parasites (nematodes, worms)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Blepharis, a genus of plants in the family Acanthaceae, has been used in traditional medicine across Africa and parts of Asia for various ailments, including as a remedy for parasitic infections such as those caused by nematodes and worms. Ethnobotanical records indicate that local healers have prepared decoctions or infusions from Blepharis leaves or roots to treat intestinal worms and other parasitic infestations. For example, in Ethiopia and some regions of India, Blepharis species are cited in folk medicine for their anthelmintic properties. However, the majority of published literature on Blepharis focuses on its antimicrobial, anti-inflammatory, and antioxidant effects, with limited direct scientific studies on its efficacy against nematodes or helminths.

A few preliminary in vitro and animal studies suggest that extracts from certain Blepharis species may have some anthelmintic activity, but these studies are sparse and generally lack robust controls or comparisons to established treatments. No clinical trials have validated its use in humans for parasitic infections as of 2024. Thus, while the use of Blepharis for treating parasites is supported by traditional knowledge, scientific evidence is limited, and the strength of evidence remains modest (rated 2/5).

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