Evidence supporting the use of: Purple Tephrosia
For the health condition: Parasites (nematodes, worms)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Purple Tephrosia (Tephrosia purpurea) has a long history of use in traditional medicine, particularly in Ayurveda and folk medicine systems of India and Africa, for the treatment of intestinal parasites such as nematodes and worms. Traditional practitioners have employed extracts and decoctions of the plant for their purported anthelmintic (anti-parasitic) properties. The roots, seeds, and leaves are commonly prepared for this purpose.

Scientific research has offered some support for these traditional claims. Several in vitro and in vivo studies have demonstrated that extracts of Tephrosia purpurea possess activity against parasitic worms. For example, laboratory studies have shown that certain alkaloids, flavonoids, and rotenoids present in the plant can immobilize or kill nematodes and other helminths. However, most of these studies have been conducted on animal models or in laboratory settings, and there is a lack of large-scale clinical trials in humans to conclusively establish efficacy and safety.

In summary, the use of Purple Tephrosia to treat parasitic infections is rooted primarily in traditional practice, with moderate scientific evidence (mainly preclinical) supporting its anthelmintic potential. Caution is advised, as further research is needed to verify its effectiveness and safety for human use.

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