Evidence supporting the use of: Stemona
For the health condition: Parasites (nematodes, worms)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Stemona spp., particularly Stemona tuberosa, have been used in traditional Chinese medicine and other Asian medical systems for a variety of conditions, including as an anthelmintic (anti-parasitic) agent. Historical records such as the Chinese pharmacopoeia and traditional herbal compendia mention the use of Stemona roots to expel parasites, especially intestinal worms (nematodes). The primary use is based on centuries of empirical traditional practice rather than on extensive modern pharmacological studies.

There is some laboratory evidence suggesting that extracts from Stemona species may have activity against certain parasites, particularly nematodes, in vitro and in animal models. Studies have identified compounds such as alkaloids (e.g., stemonine, tuberostemonine) that may possess anti-parasitic properties, but robust clinical data in humans are lacking. The degree of scientific validation remains limited, and most references are to traditional usage rather than peer-reviewed clinical trials.

In summary, the use of Stemona for treating or supporting the treatment of nematode and worm infections is primarily justified by traditional use, with some preliminary laboratory evidence but insufficient high-quality scientific validation. The overall evidence rating for this indication is 2 out of 5.

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