Evidence supporting the use of: Bacopa glycoside (unspecified)
For the body system: Parasympathetic Nervous System
Synopsis
Source of validity: Traditional
Rating (out of 5): 3
Bacopa monnieri, the plant source of Bacopa glycosides (notably bacosides A and B), has a long history of use in Ayurvedic medicine as a "medhya rasayana"—a rejuvenator for the mind and nervous system. Traditional texts and practices describe Bacopa as a nervine tonic, used to enhance memory, cognition, and general neurological health, which corresponds broadly to support of the parasympathetic nervous system (PNS). While Bacopa is not specifically described in historical texts as targeting the PNS, its calming and adaptogenic properties suggest traditional use for supporting relaxation, stress resilience, and nervous system balance—functions mediated by the PNS.
Scientific studies have largely focused on Bacopa's cognitive and neuroprotective effects, with some research indicating it may reduce stress and anxiety in animal models and humans. These calming effects could indirectly support parasympathetic activity by reducing the physiological activation of the sympathetic ("fight or flight") system. However, direct evidence of Bacopa glycosides specifically enhancing or supporting the parasympathetic nervous system is limited. Some studies report changes in neurotransmitter levels and antioxidant effects in the brain, which could theoretically influence autonomic balance.
In summary, Bacopa glycosides are used primarily on the basis of traditional knowledge to support nervous system health, with indirect evidence that may relate to parasympathetic function. Strong, direct scientific validation for PNS support is lacking at this time.
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Specific Neurotransmitters