Evidence supporting the use of: Bacosides (mixed)
For the body system: Parasympathetic Nervous System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Bacosides are the primary active compounds found in the herb Bacopa monnieri, commonly known as Brahmi. The use of Bacopa in supporting the nervous system, including the parasympathetic nervous system, is primarily rooted in traditional Ayurvedic medicine. Historically, Bacopa has been used as a "medhya rasayana"—an herb believed to enhance memory, cognition, and calmness. While Ayurvedic texts do not specify the parasympathetic nervous system by name (as it was not a known concept at the time), Bacopa was recommended for conditions associated with stress, anxiety, and mental fatigue, which are now understood to involve parasympathetic activity. Modern studies have focused on Bacopa’s cognitive and anxiolytic effects, with some evidence showing that standardized extracts may reduce anxiety and improve memory in both animal and limited human studies. However, specific targeting or enhancement of the parasympathetic nervous system by bacosides has not been robustly demonstrated in scientific literature. The traditional use, combined with preliminary evidence for stress modulation, forms the basis for claims regarding support for the parasympathetic nervous system, but direct, high-quality clinical evidence specific to this system is lacking. Thus, the justification for using bacosides for this purpose is primarily traditional, with some supportive but indirect scientific rationale.
More about Bacosides (mixed)
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