Evidence supporting the use of: Cocoa
For the body system: Parasympathetic Nervous System
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Cocoa, derived from the seeds of the Theobroma cacao tree, has been investigated for its effects on the nervous system, including the parasympathetic branch. Scientific studies have shown that cocoa is rich in flavonoids, especially epicatechin, which may influence cardiovascular and autonomic nervous system function. Research indicates that consumption of cocoa flavonoids can improve endothelial function and increase vagal (parasympathetic) tone, as measured by heart rate variability (HRV) in both healthy individuals and those with cardiovascular risk factors. Higher HRV is generally associated with increased parasympathetic (rest-and-digest) activity. Additionally, cocoa’s polyphenols may reduce stress-induced cortisol release and modulate neurotransmitter systems, such as serotonin, which may further support parasympathetic activity.
However, while several studies show acute effects of cocoa on HRV and stress reduction, the long-term significance and mechanisms remain under investigation. Most evidence is based on short-term interventions or surrogate markers rather than direct clinical outcomes. Systematic reviews and meta-analyses suggest potential benefits, but more robust, long-term studies are needed to confirm these effects. In summary, there is moderate scientific evidence (rated 3 out of 5) for cocoa’s support of the parasympathetic nervous system, primarily via improvements in HRV and stress modulation.
Other ingredients that support Parasympathetic Nervous System
7,8-DihydroxyflavoneAcetylcholine
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
basil
bergamot
beta caryophyllene
biota seed
brahmi
bасора
Calea zacatechichi
California poppy
Capitate Valerian
cardamom
catnip
chamomile
choline
chrysanthemum
citrus sinensis (proprietary)
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowage seed
DHA (docosahexaenoic acid)
dioscorea
electrolytes blend (proprietary)
fava bean
GABA (gamma aminobutyric acid)
galantamine
gardenia
gastrodia
gastrodin
ginseng
Ginsenosides
guayusa
haliotis
herbal blend (proprietary)
Honokiol
hops
huperzine A
Jatamansi
jiaogulan
jujube
jujubosides
kava
kavalactones
kudzu
L-glycine
L-taurine
L-theanine
lactium casein decapeptide
lavender
lemon balm
lemongrass
lion's mane
lotus seed
lupulinum
magnesium
magnolia
Motherwort
Mulungu
Mushroom
Nymphaea caerulea
passionflower
phytocannabinoids
Polygala
Rauvolfia
relora® (proprietary)
rosavins
sceletium
Shankhpushpi
skullcap
Szechuan lovage
Tagara
Valerenic acid
Valerian root
vitamin B
Waterhyssop
Withanolides
Ylang ylang
Other body systems supported by cocoa
ArteriesBlood
Brain
Circulatory System
Gastrointestinal Tract
Heart
Immune System
Nerves
Parasympathetic Nervous System
Skin
