Evidence supporting the use of: Gastrodin
For the body system: Parasympathetic Nervous System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Gastrodin is a bioactive compound derived from the traditional Chinese medicinal herb Gastrodia elata. There is emerging scientific evidence that Gastrodin may influence the autonomic nervous system, including the parasympathetic branch. Preclinical studies, primarily in animal models, suggest that Gastrodin has neuroprotective effects, can modulate neurotransmitter levels (such as GABA and acetylcholine), and may reduce oxidative stress and inflammation in the nervous system. Some studies indicate that Gastrodin can promote relaxation, improve cognitive function, and reduce anxiety-like behavior, which are associated with parasympathetic (rest-and-digest) activity. However, direct evidence for Gastrodin specifically supporting the parasympathetic nervous system in humans is limited. Most available data are from in vitro or animal studies, and clinical trials in humans are scarce. Traditionally, Gastrodia elata has been used in Chinese medicine for calming the mind, treating headaches, and alleviating neurological disorders, which aligns conceptually with parasympathetic support, but modern scientific validation is still developing. Overall, while there is a scientific basis for Gastrodin impacting nervous system health, the current level of evidence specifically supporting its use for the parasympathetic nervous system is moderate and primarily preclinical.

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