Evidence supporting the use of: Magnesiium
For the body system: Parasympathetic Nervous System
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Magnesium is scientifically recognized for its role in supporting the parasympathetic nervous system (PNS), which is responsible for "rest and digest" functions in the body. Magnesium acts as a natural calcium antagonist and plays a crucial role in nerve transmission, muscle relaxation, and the modulation of neurotransmitter release. Several studies have demonstrated that magnesium deficiency can lead to heightened sympathetic nervous system activity (the "fight or flight" response), increased stress, and reduced vagal tone (a measure of PNS activity). Conversely, adequate magnesium levels are associated with improved relaxation, reduced stress responses, and enhanced parasympathetic function.
Clinical trials have shown that magnesium supplementation can reduce symptoms of anxiety and improve sleep quality, both of which are linked to parasympathetic activation. Magnesium is also involved in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis and may blunt the release of stress hormones such as cortisol. Overall, the scientific evidence supports the use of magnesium to promote parasympathetic nervous system activity, particularly by helping to balance autonomic nervous system function and counteract the effects of chronic stress.
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