Evidence supporting the use of: Mulungu
For the body system: Parasympathetic Nervous System
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Erythrina mulungu, commonly known as Mulungu, is a tree native to South America whose bark and leaves have been used traditionally in Brazilian herbal medicine. Historically, Mulungu has been used as a calming agent, sleep aid, and for relief of anxiety and stress—functions associated with supporting parasympathetic nervous system activity (promoting relaxation and "rest-and-digest" states). The traditional use is rooted in indigenous and folk practices, particularly in Brazil, where preparations of the bark are consumed as teas or tinctures.
Scientific research on Mulungu is still limited. Some in vitro and animal studies have suggested that alkaloids found in Erythrina mulungu may have anxiolytic (anxiety-reducing) and sedative effects, likely by modulating neurotransmitter systems such as GABAergic pathways, which are involved in parasympathetic activation. However, there are no robust clinical trials in humans substantiating its efficacy or safety for supporting the parasympathetic nervous system directly. Thus, while its use is justified by tradition and partially supported by preliminary pharmacological findings, strong scientific validation is lacking.
In summary, Mulungu is traditionally used to promote calm and relaxation, aligning with the aims of supporting the parasympathetic nervous system, but the evidence is primarily traditional with only limited scientific support.
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