Evidence supporting the use of: Valerian
For the body system: Parasympathetic Nervous System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Valerian (Valeriana officinalis) has a long history of traditional use as a calming herb, especially in European herbal medicine. It has been used for centuries to promote relaxation, reduce anxiety, and support sleep, all of which are functions associated with the parasympathetic nervous system (PNS). The PNS is responsible for the body’s "rest and digest" activities, which are supported by calming and sedative actions.

Historically, valerian root was recommended by Hippocrates and Galen for insomnia and nervous conditions. Its use as a mild sedative and anxiolytic persisted through the Middle Ages and into modern herbal practice. The traditional rationale for its use centers on its observed calming effects, which align with the activation of parasympathetic responses.

Some scientific studies have investigated valerian’s effects on sleep and anxiety, with mixed results. While certain trials suggest mild benefits for sleep quality and latency, the evidence is inconsistent and often hampered by methodological limitations. The precise mechanisms are not fully understood, but valerian is thought to interact with GABAergic systems in the brain, which are also involved in parasympathetic activity. However, direct evidence that valerian specifically supports the parasympathetic nervous system per se is lacking.

In summary, valerian’s use is primarily justified by a substantial tradition of herbal medicine, with some supporting, but inconclusive, scientific evidence for related calming and sedative effects.

More about Valerian
More about Parasympathetic Nervous System

Other body systems supported by Valerian

Brain
GABA
Nerves
Parasympathetic Nervous System

Products containing Valerian

We currently have no products on Vitabase that contain this ingredient.