Evidence supporting the use of: Antioxidant (unspecified)
For the health condition: Parkinson's Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Antioxidants have been investigated as a potential supportive therapy in Parkinson's Disease (PD) due to the role of oxidative stress in the pathogenesis of the condition. Oxidative stress refers to cellular damage caused by free radicals, and several studies have shown that markers of oxidative damage are elevated in the brains of people with PD. This has led to the hypothesis that antioxidants—substances that neutralize free radicals—might slow disease progression or alleviate symptoms.
While some antioxidants like vitamin E, vitamin C, coenzyme Q10, and others have been explored in clinical trials, the results have been mixed or negative. For example, large randomized controlled trials with vitamin E and coenzyme Q10 did not demonstrate a significant benefit in slowing the progression of PD. Systematic reviews and meta-analyses generally conclude that, as of now, there is insufficient evidence to recommend antioxidant supplementation as an effective treatment for Parkinson's Disease. However, research into specific antioxidants and their mechanisms continues, and dietary intake of antioxidants as part of a healthy diet is sometimes encouraged, though not as a replacement for established therapies.
In summary, while there is a scientific rationale and substantial research interest in the use of antioxidants for PD, clinical evidence supporting their efficacy is limited and does not support their use as a primary or adjunctive therapy at this time.
More about Antioxidant (unspecified)
More about Parkinson's Disease
Other ingredients used for Parkinson's Disease
acetyl l-carnitineakkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
l-carnosine
l-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Other health conditions supported by Antioxidant (unspecified)
Age SpotsAging (prevention)
Alzheimer's Disease
Arteriosclerosis
Arthritis
Asthma
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cataracts
Chemotherapy (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Circulation (to the brain)
Depression
Diabetes
Diabetic Retinopathy
Fatty Liver Disease
Free Radical Damage
Gastritis
Gingivitis
Heart (weakness)
Hypertension
Inflammation
Inflammatory Bowel Disorders
Liver Detoxification
Lupus
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Migraine
Parkinson's Disease
Radiation Sickness
Wrinkles