Evidence supporting the use of: Astragalin
For the health condition: Parkinson's Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 1
Astragalin is a natural flavonoid compound found in various plants, including Kaempferia galanga and green tea. While Astragalin has been studied for a variety of pharmacological effects, its use in Parkinson’s Disease (PD) is not rooted in traditional medicine practices, but rather in recent preclinical research. A few animal and cell studies have indicated that Astragalin may have neuroprotective properties relevant to PD, such as reducing oxidative stress, inhibiting neuroinflammation, and protecting dopaminergic neurons from toxin-induced injury. For example, a 2022 study in a mouse model of PD suggested that Astragalin could attenuate motor deficits and dopaminergic neuron loss, likely via its antioxidant effects and modulation of signaling pathways involved in neuronal survival.1 However, these findings are preliminary and have not yet been translated into robust clinical trials in humans. There are currently no well-designed human studies or regulatory approvals supporting Astragalin’s use for PD. Thus, while there is some scientific basis for further research, the evidence remains weak (rated 1/5) and should not be considered validated or recommended for clinical use at this time.
1. Zhang W, et al. "Astragalin Attenuates Neurodegeneration in MPTP-Induced Parkinson's Disease Models via Suppressing Oxidative Stress and Neuroinflammation." Neurochemical Research. 2022.
Other ingredients used for Parkinson's Disease
acetyl l-carnitineakkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
l-carnosine
l-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Other health conditions supported by Astragalin
ArthritisAsthma
Autoimmune Disorders
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Colitis
Conjunctivitis
Diabetes
Diabetic Retinopathy
Fibrosis
Hepatitis
Hypertension
Inflammation
Inflammatory Bowel Disorders
Liver Detoxification
Nephritis
Osteoporosis
Parkinson's Disease
Psoriasis
Rheumatoid Arthritis
Ulcers
Wounds and Sores