Evidence supporting the use of: Astragalin
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 1

Astragalin is a natural flavonoid compound found in various plants, including Kaempferia galanga and green tea. While Astragalin has been studied for a variety of pharmacological effects, its use in Parkinson’s Disease (PD) is not rooted in traditional medicine practices, but rather in recent preclinical research. A few animal and cell studies have indicated that Astragalin may have neuroprotective properties relevant to PD, such as reducing oxidative stress, inhibiting neuroinflammation, and protecting dopaminergic neurons from toxin-induced injury. For example, a 2022 study in a mouse model of PD suggested that Astragalin could attenuate motor deficits and dopaminergic neuron loss, likely via its antioxidant effects and modulation of signaling pathways involved in neuronal survival.1 However, these findings are preliminary and have not yet been translated into robust clinical trials in humans. There are currently no well-designed human studies or regulatory approvals supporting Astragalin’s use for PD. Thus, while there is some scientific basis for further research, the evidence remains weak (rated 1/5) and should not be considered validated or recommended for clinical use at this time.

1. Zhang W, et al. "Astragalin Attenuates Neurodegeneration in MPTP-Induced Parkinson's Disease Models via Suppressing Oxidative Stress and Neuroinflammation." Neurochemical Research. 2022.

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Other ingredients used for Parkinson's Disease

1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Acetyl L-carnitine
Agmatine
Akkermansia muciniphila
algal oil
AMP-activated protein kinase (AMPK)
apigenin
ashwagandha
astragalin
bacoside
baicalein
baicalin
beta caryophyllene
biopterin
black garlic
brahmi
broad bean
butyrate triglyceride
C-phycocyanin
cannabidiol
carnosic acid
catalpol
catechins
citicoline
coenzyme Q10 (CoQ10)
creatine
curcumin
decarboxylase
DHA (docosahexaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ergothioneine
fava bean
ferulic acid
fisetin
fish oil
fo-ti
gastrodin
ginkgo biloba
Ginsenosides
Glucoraphanin
Glycosphingolipids
gotu kola
green tea
Gypenoside
Haematococcus pluvialis
hericium mushroom
Honokiol
icariin
inosine
isoliquiritigenin
Jatamansi
Kaempferol
L-carnosine
L-glutathione
lingzhi
lion's mane
luteolin
magnolol
mangiferin
medium chain triglycerides (MCT)
Melatonin
Myricetin
N-acetyl-cysteine (NAC)
NADH
nicotinamide riboside
Nobiletin
Oleuropein
omega-3 fatty acids
paeoniflorin
Palmitoylethanolamide (PEA)
phosphatidylserine
Phosphocreatine
phytocannabinoids
Puerain
Puerarin
pyrroloquinoline quinone
quercetin
resveratrol
Salidroside
Salvianolic acid
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Shilajit
specialized pro-resolving mediators (SPMs)
spirulina
Sulforaphane
sulforaphane glucosinolate
Tanshinone
Trehalose
Triacetyluridine
Tumerone
ubiquinol
Uncaria
Urolithin A
velvet bean
vitamin D
vitamin D3
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone
β-nicotinamide mononucleotide (NMN)

Products containing astragalin

We currently have no products on Vitabase that contain this ingredient.