Evidence supporting the use of: Baicalin
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Baicalin is a flavonoid compound primarily derived from the roots of Scutellaria baicalensis (Chinese skullcap), a traditional herbal medicine. Its use in Parkinson's Disease (PD) is not rooted in traditional medicine but is instead supported by emerging preclinical scientific research. Several in vitro and animal studies suggest that baicalin may have neuroprotective properties relevant to PD. These effects are mainly attributed to its antioxidant, anti-inflammatory, and anti-apoptotic actions. For instance, studies in rodent models of PD (such as those induced by MPTP or 6-OHDA toxins) have demonstrated that baicalin administration can attenuate dopaminergic neuron loss in the substantia nigra, reduce oxidative stress markers, and decrease levels of pro-inflammatory cytokines. Mechanistically, baicalin is thought to modulate pathways such as Nrf2/ARE for antioxidant defense and inhibit microglial activation to reduce neuroinflammation. However, no robust human clinical trials have confirmed these benefits in people with PD. The existing evidence is limited to laboratory and animal models, and the translation to clinical efficacy remains unproven. Therefore, while there is some scientific rationale and preclinical support for baicalin as a potential adjunct in PD, the evidence is currently weak (rated 2/5) and insufficient for clinical recommendations at this time.

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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
Melatonin
N-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
apigenin
Agmatine
astragalin
biopterin
baicalein
brahmi
broad bean
bacoside
baicalin
catalpol
creatine
C-phycocyanin
cannabidiol
carnosic acid
decarboxylase
ergothioneine
eicosapentaenoic acid
fo-ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
gastrodin
Haematococcus pluvialis
Honokiol
hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
mangiferin
Myricetin
magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
pyrroloquinoline quinone
Puerarin
paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
Trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing baicalin

We currently have no products on Vitabase that contain this ingredient.