Evidence supporting the use of: C-Phycocyanin
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

C-Phycocyanin, a biliprotein pigment found in Spirulina and other cyanobacteria, has attracted scientific interest for its antioxidant and anti-inflammatory properties. In the context of Parkinson's Disease (PD), several preclinical studies have explored its neuroprotective potential. Animal and in vitro research suggests that C-Phycocyanin can reduce oxidative stress and inflammation, both of which are implicated in the degeneration of dopaminergic neurons characteristic of PD. For example, some studies in rodent models of PD have reported that C-Phycocyanin administration resulted in decreased neuronal loss, reduced markers of oxidative damage, and improved motor function. The proposed mechanisms include free radical scavenging, inhibition of pro-inflammatory cytokines, and protection of mitochondrial function. However, despite these promising findings in laboratory settings, there is a lack of robust clinical data in humans. No large-scale, high-quality randomized controlled trials have been published to confirm efficacy or safety of C-Phycocyanin supplementation in people with Parkinson's Disease. The current evidence base is therefore limited to basic and translational research, which, while encouraging, is insufficient to fully validate its clinical use. As such, the scientific evidence supporting C-Phycocyanin for Parkinson's Disease is preliminary. Further research, especially well-designed human trials, is necessary before it can be recommended for therapeutic use in this context.

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