Evidence supporting the use of: Cannabidiol
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabidiol (CBD), a non-psychoactive compound found in cannabis, has garnered interest as a potential adjunct therapy for Parkinson’s Disease (PD). The scientific evidence supporting its use is limited but growing. Preclinical studies in animal models suggest that CBD may possess neuroprotective, anti-inflammatory, and antioxidant properties, which could theoretically benefit neurodegenerative diseases like PD. However, clinical evidence in humans remains sparse and mostly limited to small-scale studies and case reports.

A few small randomized controlled trials and open-label studies have investigated CBD’s effects on symptoms of PD, particularly non-motor symptoms such as psychosis, sleep disturbances, and quality of life. For instance, a 2014 study by Chagas et al. found that CBD improved quality of life in PD patients without psychiatric comorbidities, though motor symptoms were unchanged. Another small study found that CBD reduced psychotic symptoms in PD patients. However, these studies often suffer from small sample sizes and methodological limitations.

Major neurological and movement disorder societies currently do not recommend CBD as a standard treatment for PD due to insufficient high-quality evidence. While the compound appears to be well-tolerated, more robust, large-scale clinical trials are necessary to determine its efficacy and safety profile in this population.

In summary, while there is some scientific rationale and preliminary positive findings, evidence is limited and not yet strong enough to justify routine use of CBD in treating Parkinson’s Disease.

More about cannabidiol
More about Parkinson's Disease

Other ingredients used for Parkinson's Disease

1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Acetyl L-carnitine
Agmatine
Akkermansia muciniphila
algal oil
AMP-activated protein kinase (AMPK)
apigenin
ashwagandha
astragalin
bacoside
baicalein
baicalin
beta caryophyllene
biopterin
black garlic
brahmi
broad bean
butyrate triglyceride
C-phycocyanin
cannabidiol
carnosic acid
catalpol
catechins
citicoline
coenzyme Q10 (CoQ10)
creatine
curcumin
decarboxylase
DHA (docosahexaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ergothioneine
fava bean
ferulic acid
fisetin
fish oil
fo-ti
gastrodin
ginkgo biloba
Ginsenosides
Glucoraphanin
Glycosphingolipids
gotu kola
green tea
Gypenoside
Haematococcus pluvialis
hericium mushroom
Honokiol
icariin
inosine
isoliquiritigenin
Jatamansi
Kaempferol
L-carnosine
L-glutathione
lingzhi
lion's mane
luteolin
magnolol
mangiferin
medium chain triglycerides (MCT)
Melatonin
Myricetin
N-acetyl-cysteine (NAC)
NADH
nicotinamide riboside
Nobiletin
Oleuropein
omega-3 fatty acids
paeoniflorin
Palmitoylethanolamide (PEA)
phosphatidylserine
Phosphocreatine
phytocannabinoids
Puerain
Puerarin
pyrroloquinoline quinone
quercetin
resveratrol
Salidroside
Salvianolic acid
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Shilajit
specialized pro-resolving mediators (SPMs)
spirulina
Sulforaphane
sulforaphane glucosinolate
Tanshinone
Trehalose
Triacetyluridine
Tumerone
ubiquinol
Uncaria
Urolithin A
velvet bean
vitamin D
vitamin D3
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone
β-nicotinamide mononucleotide (NMN)

Products containing cannabidiol

We currently have no products on Vitabase that contain this ingredient.