Evidence supporting the use of: Catalpol
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Catalpol is an iridoid glycoside primarily found in the roots of Rehmannia glutinosa, a traditional Chinese medicinal herb. Recent preclinical studies have investigated its potential neuroprotective effects in models of Parkinson's Disease (PD). In animal and cellular models, catalpol has shown the ability to reduce dopaminergic neuronal loss, decrease oxidative stress, and inhibit neuroinflammation, which are key pathological features of PD. Mechanistic studies suggest catalpol may exert its effects through antioxidative pathways, inhibition of apoptosis, and modulation of neurotrophic factors such as BDNF (Brain-Derived Neurotrophic Factor). However, it is important to note that all current evidence comes from laboratory and animal research. There are no published clinical trials in humans evaluating the efficacy or safety of catalpol for PD. While its traditional use focuses more broadly on kidney and brain health, its specific application in Parkinson's Disease is a recent development driven by scientific exploration rather than longstanding traditional practice. Therefore, while there is preliminary scientific support for catalpol’s neuroprotective potential in PD, this evidence is limited in quality and quantity, and its clinical relevance remains unproven.

More about catalpol
More about Parkinson's Disease

Other ingredients used for Parkinson's Disease

1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Acetyl L-carnitine
Agmatine
Akkermansia muciniphila
algal oil
AMP-activated protein kinase (AMPK)
apigenin
ashwagandha
astragalin
bacoside
baicalein
baicalin
beta caryophyllene
biopterin
black garlic
brahmi
broad bean
butyrate triglyceride
C-phycocyanin
cannabidiol
carnosic acid
catalpol
catechins
citicoline
coenzyme Q10 (CoQ10)
creatine
curcumin
decarboxylase
DHA (docosahexaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ergothioneine
fava bean
ferulic acid
fisetin
fish oil
fo-ti
gastrodin
ginkgo biloba
Ginsenosides
Glucoraphanin
Glycosphingolipids
gotu kola
green tea
Gypenoside
Haematococcus pluvialis
hericium mushroom
Honokiol
icariin
inosine
isoliquiritigenin
Jatamansi
Kaempferol
L-carnosine
L-glutathione
lingzhi
lion's mane
luteolin
magnolol
mangiferin
medium chain triglycerides (MCT)
Melatonin
Myricetin
N-acetyl-cysteine (NAC)
NADH
nicotinamide riboside
Nobiletin
Oleuropein
omega-3 fatty acids
paeoniflorin
Palmitoylethanolamide (PEA)
phosphatidylserine
Phosphocreatine
phytocannabinoids
Puerain
Puerarin
pyrroloquinoline quinone
quercetin
resveratrol
Salidroside
Salvianolic acid
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Shilajit
specialized pro-resolving mediators (SPMs)
spirulina
Sulforaphane
sulforaphane glucosinolate
Tanshinone
Trehalose
Triacetyluridine
Tumerone
ubiquinol
Uncaria
Urolithin A
velvet bean
vitamin D
vitamin D3
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone
β-nicotinamide mononucleotide (NMN)

Products containing catalpol

We currently have no products on Vitabase that contain this ingredient.