Evidence supporting the use of: Cysteine compounds (unspecified)
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cysteine compounds, particularly N-acetylcysteine (NAC), have been investigated for their potential to support or treat Parkinson's Disease (PD), primarily due to their antioxidant properties. The scientific rationale stems from the role of oxidative stress and glutathione depletion in the pathogenesis of PD. Cysteine is a precursor for glutathione synthesis, and NAC is a well-tolerated supplement that increases brain glutathione levels. Several small-scale clinical studies and preclinical animal models have suggested that NAC may improve mitochondrial function, reduce oxidative stress, and modulate dopamine levels. For example, a 2016 pilot clinical trial (Holmay et al.) found that intravenous and oral NAC increased brain and blood glutathione levels in PD patients. Another small randomized controlled trial (Monti et al., 2019) reported improvements in dopamine transporter binding and self-reported symptoms. However, these studies are limited by small sample sizes, short durations, and methodological constraints. There is currently insufficient evidence from large, well-controlled clinical trials to definitively recommend cysteine compounds for PD. Thus, while there is a scientific basis for interest and some early-stage human data, the quality and quantity of evidence supporting their use in PD remain low to moderate, and further research is needed.

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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Fo-Ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
Gastrodin
Haematococcus pluvialis
Honokiol
Hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
Mangiferin
Myricetin
Magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
Pyrroloquinoline Quinone
Puerarin
Paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing Cysteine compounds (unspecified)

We currently have no products on Vitabase that contain this ingredient.