Evidence supporting the use of: Ginkgo biloba
For the health condition: Parkinson's Disease

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginkgo biloba is sometimes used as an adjunctive supplement in the context of Parkinson's Disease (PD), primarily due to its purported neuroprotective and antioxidant properties. Preclinical studies suggest that extracts from Ginkgo biloba leaves, especially standardized forms like EGb 761, may protect dopaminergic neurons against oxidative stress—a key mechanism in PD pathogenesis. Some animal studies have shown that Ginkgo biloba can attenuate neurodegeneration in models of Parkinson's Disease, possibly by reducing oxidative damage, modulating mitochondrial function, and inhibiting apoptosis. However, robust clinical evidence in humans is limited. A few small-scale clinical trials and case reports have explored the adjunctive use of Ginkgo biloba in PD patients, with mixed results. Some studies report mild improvements in symptoms such as cognitive performance and activities of daily living, but these findings are not consistently replicated in larger, high-quality randomized controlled trials. Additionally, systematic reviews and meta-analyses generally conclude that while Ginkgo biloba is well-tolerated, there is insufficient evidence to recommend its use as a standard therapy in Parkinson's Disease. Traditional use of Ginkgo biloba in Chinese medicine is more focused on circulatory and cognitive conditions rather than Parkinson's specifically. Therefore, while scientific interest exists, and some preliminary data are available, the quality and quantity of evidence supporting Ginkgo biloba for PD remain modest, meriting a low-to-moderate rating.

More about ginkgo biloba
More about Parkinson's Disease

Other ingredients used for Parkinson's Disease

1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Acetyl L-carnitine
Agmatine
Akkermansia muciniphila
algal oil
AMP-activated protein kinase (AMPK)
apigenin
ashwagandha
astragalin
bacoside
baicalein
baicalin
beta caryophyllene
biopterin
black garlic
brahmi
broad bean
butyrate triglyceride
C-phycocyanin
cannabidiol
carnosic acid
catalpol
catechins
citicoline
coenzyme Q10 (CoQ10)
creatine
curcumin
decarboxylase
DHA (docosahexaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ergothioneine
fava bean
ferulic acid
fisetin
fish oil
fo-ti
gastrodin
ginkgo biloba
Ginsenosides
Glucoraphanin
Glycosphingolipids
gotu kola
green tea
Gypenoside
Haematococcus pluvialis
hericium mushroom
Honokiol
icariin
inosine
isoliquiritigenin
Jatamansi
Kaempferol
L-carnosine
L-glutathione
lingzhi
lion's mane
luteolin
magnolol
mangiferin
medium chain triglycerides (MCT)
Melatonin
Myricetin
N-acetyl-cysteine (NAC)
NADH
nicotinamide riboside
Nobiletin
Oleuropein
omega-3 fatty acids
paeoniflorin
Palmitoylethanolamide (PEA)
phosphatidylserine
Phosphocreatine
phytocannabinoids
Puerain
Puerarin
pyrroloquinoline quinone
quercetin
resveratrol
Salidroside
Salvianolic acid
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Shilajit
specialized pro-resolving mediators (SPMs)
spirulina
Sulforaphane
sulforaphane glucosinolate
Tanshinone
Trehalose
Triacetyluridine
Tumerone
ubiquinol
Uncaria
Urolithin A
velvet bean
vitamin D
vitamin D3
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone
β-nicotinamide mononucleotide (NMN)