Evidence supporting the use of: Ginsenosides
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginsenosides are the primary active compounds in ginseng (Panax ginseng) and have been investigated for their potential neuroprotective effects, including in Parkinson’s Disease (PD). Preclinical studies, mainly in cell cultures and animal models, suggest that certain ginsenosides (such as Rg1, Rb1, and Rd) may exert neuroprotective effects by reducing oxidative stress, inhibiting apoptosis (cell death), modulating neuroinflammation, and improving mitochondrial function—all processes implicated in PD pathophysiology. Some studies have demonstrated that ginsenosides can protect dopaminergic neurons from toxins used to model PD in animals, and may improve motor symptoms in these models.

However, human clinical evidence is minimal. There are no large-scale, high-quality randomized controlled trials (RCTs) assessing the efficacy of ginsenosides in treating or slowing the progression of Parkinson’s Disease in humans. Most evidence comes from laboratory and animal studies, which do not always translate to clinical efficacy in humans. Because of this, while there is a scientific basis for ongoing research, the current level of evidence supporting the use of ginsenosides for Parkinson’s Disease is weak (rated 2 out of 5). Ginsenosides are not considered a standard or established treatment for PD, but ongoing preclinical research supports further exploration.

More about Ginsenosides
More about Parkinson's Disease

Other ingredients used for Parkinson's Disease

1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Acetyl L-carnitine
Agmatine
Akkermansia muciniphila
algal oil
AMP-activated protein kinase (AMPK)
apigenin
ashwagandha
astragalin
bacoside
baicalein
baicalin
beta caryophyllene
biopterin
black garlic
brahmi
broad bean
butyrate triglyceride
C-phycocyanin
cannabidiol
carnosic acid
catalpol
catechins
citicoline
coenzyme Q10 (CoQ10)
creatine
curcumin
decarboxylase
DHA (docosahexaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ergothioneine
fava bean
ferulic acid
fisetin
fish oil
fo-ti
gastrodin
ginkgo biloba
Ginsenosides
Glucoraphanin
Glycosphingolipids
gotu kola
green tea
Gypenoside
Haematococcus pluvialis
hericium mushroom
Honokiol
icariin
inosine
isoliquiritigenin
Jatamansi
Kaempferol
L-carnosine
L-glutathione
lingzhi
lion's mane
luteolin
magnolol
mangiferin
medium chain triglycerides (MCT)
Melatonin
Myricetin
N-acetyl-cysteine (NAC)
NADH
nicotinamide riboside
Nobiletin
Oleuropein
omega-3 fatty acids
paeoniflorin
Palmitoylethanolamide (PEA)
phosphatidylserine
Phosphocreatine
phytocannabinoids
Puerain
Puerarin
pyrroloquinoline quinone
quercetin
resveratrol
Salidroside
Salvianolic acid
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Shilajit
specialized pro-resolving mediators (SPMs)
spirulina
Sulforaphane
sulforaphane glucosinolate
Tanshinone
Trehalose
Triacetyluridine
Tumerone
ubiquinol
Uncaria
Urolithin A
velvet bean
vitamin D
vitamin D3
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone
β-nicotinamide mononucleotide (NMN)

Products containing Ginsenosides

We currently have no products on Vitabase that contain this ingredient.