Evidence supporting the use of: Ginsenosides (unspecified)
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginsenosides, the primary active compounds in ginseng (Panax species), have been investigated for their neuroprotective effects, including potential applications in Parkinson's Disease (PD). Preclinical studies (in vitro and in vivo animal models) suggest that ginsenosides may exert beneficial effects in PD through anti-inflammatory, antioxidant, and anti-apoptotic mechanisms. Specifically, ginsenosides such as Rg1, Rb1, and Rd have demonstrated the ability to protect dopaminergic neurons against toxins like MPTP and 6-OHDA, which are commonly used to model PD in animals. These effects appear to involve modulation of neuroinflammatory pathways, reduction of oxidative stress, and inhibition of neuronal cell death.

However, human clinical evidence remains limited. Most published research consists of animal or cellular studies, with only a few small-scale pilot trials in humans, often lacking rigorous controls or sufficient sample sizes. As such, while there is a scientific rationale and some promising preclinical data supporting the use of ginsenosides in PD, the overall evidence base is weak, and high-quality clinical trials are needed to confirm efficacy and safety in humans. Therefore, the use of ginsenosides for Parkinson’s Disease is supported by scientific investigation, but the current level of evidence is low (rated 2 out of 5).

More about Ginsenosides (unspecified)
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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Fo-Ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
Gastrodin
Haematococcus pluvialis
Honokiol
Hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
Mangiferin
Myricetin
Magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
Pyrroloquinoline Quinone
Puerarin
Paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing Ginsenosides (unspecified)

We currently have no products on Vitabase that contain this ingredient.