Evidence supporting the use of: Omega-3
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been explored as a potential adjunct therapy in Parkinson's Disease (PD) due to their anti-inflammatory and neuroprotective properties observed in preclinical studies. Experimental models suggest that omega-3s can reduce neuroinflammation, oxidative stress, and neuronal apoptosis, all of which are implicated in the progression of PD. Some small human studies and pilot trials have investigated omega-3 supplementation in people with Parkinson's Disease. For example, a 2008 randomized controlled trial (RCCT) by da Silva et al. found that omega-3 supplementation, alongside standard antidepressant therapy, improved depressive symptoms in PD patients over 12 weeks. However, the trial did not demonstrate a significant benefit in core motor symptoms of the disease. Other clinical trials have been small, short-term, or inconclusive regarding omega-3's impact on disease progression or motor function, and systematic reviews conclude that evidence for omega-3 supplementation as a disease-modifying treatment in PD is limited and inconsistent. No major clinical guidelines recommend omega-3s specifically for PD management. While omega-3s are generally regarded as safe and may support overall brain and cardiovascular health, robust evidence supporting their efficacy for Parkinson’s Disease specifically remains insufficient. More large-scale, long-term randomized controlled trials are needed to clarify their role in PD.

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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Fo-Ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
Gastrodin
Haematococcus pluvialis
Honokiol
Hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
Mangiferin
Myricetin
Magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
Pyrroloquinoline Quinone
Puerarin
Paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing Omega-3

We currently have no products on Vitabase that contain this ingredient.