Evidence supporting the use of: Resveratrol analogue
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Resveratrol analogues have been investigated in preclinical models for their potential neuroprotective effects in Parkinson’s Disease (PD). The interest is primarily rooted in the well-characterized antioxidant, anti-inflammatory, and mitochondrial protective properties of resveratrol and its structurally similar analogues. Several in vitro and animal studies suggest that resveratrol analogues can attenuate dopaminergic neuronal loss, reduce oxidative stress, and modulate neuroinflammation—hallmarks of PD pathology. For example, studies using MPTP or 6-OHDA-induced PD models in mice and rats demonstrate that resveratrol analogues may improve motor function and protect against neuronal degeneration via the activation of pathways such as SIRT1 and Nrf2. However, there is currently no robust clinical evidence from randomized controlled trials supporting the use of resveratrol analogues for PD in humans. Most data are limited to laboratory and animal research, and issues such as bioavailability and dosing remain unresolved. As such, while there is a scientific rationale and promising preclinical evidence, clinical validation is lacking. Resveratrol analogues are not standard or widely endorsed treatments for PD, and their use is not based on historical or traditional medicine practices. The evidence is therefore rated as 2, indicating promising laboratory research but insufficient human data.

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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Fo-Ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
Gastrodin
Haematococcus pluvialis
Honokiol
Hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
Mangiferin
Myricetin
Magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
Pyrroloquinoline Quinone
Puerarin
Paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing Resveratrol analogue

We currently have no products on Vitabase that contain this ingredient.