Evidence supporting the use of: Tanshinone
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Tanshinone is a class of bioactive compounds derived from the roots of Salvia miltiorrhiza (Danshen), a traditional Chinese medicinal herb. In recent years, tanshinones—particularly tanshinone I and tanshinone IIA—have been investigated in preclinical studies for their neuroprotective effects, including their potential in models of Parkinson's Disease (PD). Laboratory and animal studies suggest that tanshinones may exert beneficial effects through several mechanisms relevant to PD: antioxidative stress, anti-inflammatory activity, mitochondrial protection, inhibition of neuronal apoptosis, and modulation of dopaminergic neuron survival. However, the evidence supporting the use of tanshinones in PD is currently limited to in vitro studies and animal models. For example, some studies have reported that tanshinone IIA can attenuate dopaminergic neuron loss and reduce oxidative damage in rodent models of PD induced by 6-hydroxydopamine (6-OHDA) or MPTP. These findings suggest a potential neuroprotective effect, but no high-quality clinical trials in humans have been published to confirm efficacy or safety for PD patients. In summary, while there is a scientific rationale and early experimental support for investigating tanshinones in Parkinson’s Disease, the evidence is preliminary and does not yet justify clinical use. Further research, including well-controlled human studies, is needed before tanshinones can be recommended for this indication.

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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Fo-Ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
Gastrodin
Haematococcus pluvialis
Honokiol
Hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
Mangiferin
Myricetin
Magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
Pyrroloquinoline Quinone
Puerarin
Paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing Tanshinone

We currently have no products on Vitabase that contain this ingredient.