Evidence supporting the use of: Thickeners
For the health condition: Parkinson's Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Thickeners, such as modified cornstarch, xanthan gum, or commercial thickening powders, are scientifically validated for use in managing dysphagia (difficulty swallowing) in Parkinson's Disease (PD). Dysphagia is a common non-motor symptom in PD, arising from impaired coordination of the muscles involved in swallowing. This can increase the risk of aspiration (food or liquid entering the airway), leading to pneumonia—a major cause of morbidity and mortality in PD patients.
Thickened fluids reduce the speed at which liquids travel through the oropharynx, allowing individuals more time to coordinate swallowing and protect the airway. Multiple clinical studies and systematic reviews support the use of thickeners to decrease aspiration risk in PD and other neurogenic dysphagia populations. The 2021 European Society for Swallowing Disorders and the European Union Geriatric Medicine Society guidelines, as well as American Speech-Language-Hearing Association (ASHA) recommendations, endorse the use of thickened liquids for patients with demonstrated swallowing difficulties.
However, while thickeners are effective at reducing aspiration, there are ongoing discussions about patient acceptance, hydration status, and potential risks (such as increased pharyngeal residue), meaning their use should be individualized and guided by a speech-language pathologist or swallowing specialist. In summary, thickeners have a strong scientific basis for use in supporting PD patients with swallowing difficulties but are not a treatment for Parkinson's Disease itself.
Other ingredients used for Parkinson's Disease
acetyl l-carnitineakkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
l-carnosine
l-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid