Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Triacetyluridine (TAU) is a prodrug of uridine, a naturally occurring nucleoside. Its use in Parkinson’s Disease (PD) is grounded in scientific research, though the evidence is preliminary and not conclusive. The rationale for using triacetyluridine in PD comes from preclinical and early clinical studies suggesting that uridine supplementation may help support dopamine synthesis and neuronal membrane phospholipid production—both of which are implicated in the pathophysiology of PD. In animal models, combinations of uridine (as triacetyluridine), omega-3 fatty acids (like DHA), and choline have shown potential to increase dopamine release, improve synaptic function, and possibly ameliorate motor symptoms related to PD. A small number of human studies have explored uridine supplementation (often as part of a multi-nutrient approach) in PD patients, but results are mixed and sample sizes are limited. There is currently no large-scale clinical trial demonstrating a clear and consistent benefit of triacetyluridine for the treatment or support of Parkinson’s Disease. Nevertheless, the mechanistic rationale and some positive signals from animal and early human studies provide a modest scientific basis for its consideration. Triacetyluridine is not part of standard PD guidelines, and its use is considered experimental. Patients or clinicians should approach its use cautiously and always in consultation with a healthcare professional.

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Other ingredients used for Parkinson's Disease

1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Acetyl L-carnitine
Agmatine
Akkermansia muciniphila
algal oil
AMP-activated protein kinase (AMPK)
apigenin
ashwagandha
astragalin
bacoside
baicalein
baicalin
beta caryophyllene
biopterin
black garlic
brahmi
broad bean
butyrate triglyceride
C-phycocyanin
cannabidiol
carnosic acid
catalpol
catechins
citicoline
coenzyme Q10 (CoQ10)
creatine
curcumin
decarboxylase
DHA (docosahexaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ergothioneine
fava bean
ferulic acid
fisetin
fish oil
fo-ti
gastrodin
ginkgo biloba
Ginsenosides
Glucoraphanin
Glycosphingolipids
gotu kola
green tea
Gypenoside
Haematococcus pluvialis
hericium mushroom
Honokiol
icariin
inosine
isoliquiritigenin
Jatamansi
Kaempferol
L-carnosine
L-glutathione
lingzhi
lion's mane
luteolin
magnolol
mangiferin
medium chain triglycerides (MCT)
Melatonin
Myricetin
N-acetyl-cysteine (NAC)
NADH
nicotinamide riboside
Nobiletin
Oleuropein
omega-3 fatty acids
paeoniflorin
Palmitoylethanolamide (PEA)
phosphatidylserine
Phosphocreatine
phytocannabinoids
Puerain
Puerarin
pyrroloquinoline quinone
quercetin
resveratrol
Salidroside
Salvianolic acid
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Shilajit
specialized pro-resolving mediators (SPMs)
spirulina
Sulforaphane
sulforaphane glucosinolate
Tanshinone
Trehalose
Triacetyluridine
Tumerone
ubiquinol
Uncaria
Urolithin A
velvet bean
vitamin D
vitamin D3
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone
β-nicotinamide mononucleotide (NMN)

Other health conditions supported by Triacetyluridine

Memory and Brain Function
Parkinson's Disease
Peripheral Neuropathy

Products containing Triacetyluridine

We currently have no products on Vitabase that contain this ingredient.