Evidence supporting the use of: Triacetyluridine
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Triacetyluridine (TAU) is a prodrug of uridine, a naturally occurring nucleoside. Its use in Parkinson’s Disease (PD) is grounded in scientific research, though the evidence is preliminary and not conclusive. The rationale for using triacetyluridine in PD comes from preclinical and early clinical studies suggesting that uridine supplementation may help support dopamine synthesis and neuronal membrane phospholipid production—both of which are implicated in the pathophysiology of PD. In animal models, combinations of uridine (as triacetyluridine), omega-3 fatty acids (like DHA), and choline have shown potential to increase dopamine release, improve synaptic function, and possibly ameliorate motor symptoms related to PD. A small number of human studies have explored uridine supplementation (often as part of a multi-nutrient approach) in PD patients, but results are mixed and sample sizes are limited. There is currently no large-scale clinical trial demonstrating a clear and consistent benefit of triacetyluridine for the treatment or support of Parkinson’s Disease. Nevertheless, the mechanistic rationale and some positive signals from animal and early human studies provide a modest scientific basis for its consideration. Triacetyluridine is not part of standard PD guidelines, and its use is considered experimental. Patients or clinicians should approach its use cautiously and always in consultation with a healthcare professional.

More about Triacetyluridine
More about Parkinson's Disease

Other health conditions supported by Triacetyluridine

Memory and Brain Function
Parkinson's Disease
Peripheral Neuropathy

Products containing Triacetyluridine

We currently have no products on Vitabase that contain this ingredient.