Evidence supporting the use of: Tumerone
For the health condition: Parkinson's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Tumerone is a bioactive compound found in turmeric (Curcuma longa). Its use in supporting or treating Parkinson's Disease (PD) is justified by emerging scientific research, largely in preclinical settings. Animal and cell culture studies suggest that tumerone may exert neuroprotective effects. For example, a 2014 study published in Stem Cell Research & Therapy showed that aromatic tumerone promoted the proliferation and differentiation of neural stem cells in rodents, raising interest for neurodegenerative diseases like PD. Other studies have indicated that tumerone might reduce neuroinflammation and oxidative stress—two processes implicated in PD pathology.

However, this evidence is preliminary. There are no well-designed human clinical trials evaluating the efficacy or safety of tumerone in PD patients. Most findings are limited to in vitro (cell) or animal models, which may not directly translate to human benefit. Accordingly, while tumerone is sometimes included in supplements targeting brain health, its use for Parkinson’s is not established in mainstream clinical practice. The current scientific evidence supporting its use for PD is weak (rating: 2/5), and further research, especially human trials, is needed to determine its relevance in this context.

More about Tumerone
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Other ingredients used for Parkinson's Disease

Acetyl L-carnitine
Akkermansia muciniphila
algal oil
ashwagandha
beta caryophyllene
black garlic
butyrate triglyceride
catechins
citicoline
coenzyme Q10 (CoQ10)
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fava bean
fisetin
fish oil
ginkgo biloba
gotu kola
green tea
L-carnosine
L-glutathione
lion's mane
luteolin
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
phosphatidylserine
phytocannabinoids
quercetin
resveratrol
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
specialized pro-resolving mediators (SPMs)
spirulina
sulforaphane glucosinolate
ubiquinol
Urolithin A
velvet bean
vitamin D
vitamin D3
β-nicotinamide mononucleotide (NMN)
lingzhi
ferulic acid
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Apigenin
Agmatine
Astragalin
Biopterin
Baicalein
Brahmi
Broad Bean
bacoside
Baicalin
Catalpol
Creatine
C-Phycocyanin
Cannabidiol
Carnosic acid
Decarboxylase
Ergothioneine
Eicosapentaenoic Acid
Fo-Ti
Ginsenosides
Gypenoside
Glycosphingolipids
Glucoraphanin
Gastrodin
Haematococcus pluvialis
Honokiol
Hericium mushroom
inosine
isoliquiritigenin
icariin
Jatamansi
Kaempferol
Mangiferin
Myricetin
Magnolol
NADH
Nobiletin
Oleuropein
Phosphocreatine
Puerain
Pyrroloquinoline Quinone
Puerarin
Paeoniflorin
Palmitoylethanolamide (PEA)
Salidroside
Salvianolic acid
Shilajit
Sulforaphane
Tumerone
Tanshinone
trehalose
Triacetyluridine
Uncaria
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone

Products containing Tumerone

We currently have no products on Vitabase that contain this ingredient.