Evidence supporting the use of: Velvet bean
For the health condition: Parkinson's Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Velvet bean (Mucuna pruriens) has a long history of use in traditional Ayurvedic medicine for neurological disorders, including symptoms resembling Parkinson’s Disease (PD). The scientific rationale for its use in modern times is based on its high natural content of levodopa (L-dopa), the same compound used as a cornerstone therapy in conventional PD treatment. L-dopa is a precursor to dopamine, a neurotransmitter that becomes deficient in the brains of those with Parkinson’s Disease.
A number of clinical studies have investigated the efficacy of Mucuna pruriens seed preparations in PD. In a randomized, controlled, double-blind crossover trial (2004), patients with PD were given either standard levodopa or a dose-equivalent Mucuna extract. The Mucuna group had a faster onset of action and a longer duration of clinical benefit, with no significant increase in adverse effects. Several smaller trials and case reports have also found that velvet bean can reduce movement symptoms and may have a lower risk of some complications such as dyskinesias, though more research is needed.
While there is scientific validation for its efficacy—largely attributed to its L-dopa content—standardization, dosing, and long-term safety remain concerns. Nevertheless, both traditional use and modern studies support velvet bean as a viable, albeit alternative, option for PD management, especially where pharmaceutical L-dopa is unavailable or unaffordable.
Other ingredients used for Parkinson's Disease
1,3,7-Trimethylpurine-2,6-dione7,8-Dihydroxyflavone
Acetyl L-carnitine
Agmatine
Akkermansia muciniphila
algal oil
AMP-activated protein kinase (AMPK)
apigenin
ashwagandha
astragalin
bacoside
baicalein
baicalin
beta caryophyllene
biopterin
black garlic
brahmi
broad bean
butyrate triglyceride
C-phycocyanin
cannabidiol
carnosic acid
catalpol
catechins
citicoline
coenzyme Q10 (CoQ10)
creatine
curcumin
decarboxylase
DHA (docosahexaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ergothioneine
fava bean
ferulic acid
fisetin
fish oil
fo-ti
gastrodin
ginkgo biloba
Ginsenosides
Glucoraphanin
Glycosphingolipids
gotu kola
green tea
Gypenoside
Haematococcus pluvialis
hericium mushroom
Honokiol
icariin
inosine
isoliquiritigenin
Jatamansi
Kaempferol
L-carnosine
L-glutathione
lingzhi
lion's mane
luteolin
magnolol
mangiferin
medium chain triglycerides (MCT)
Melatonin
Myricetin
N-acetyl-cysteine (NAC)
NADH
nicotinamide riboside
Nobiletin
Oleuropein
omega-3 fatty acids
paeoniflorin
Palmitoylethanolamide (PEA)
phosphatidylserine
Phosphocreatine
phytocannabinoids
Puerain
Puerarin
pyrroloquinoline quinone
quercetin
resveratrol
Salidroside
Salvianolic acid
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Shilajit
specialized pro-resolving mediators (SPMs)
spirulina
Sulforaphane
sulforaphane glucosinolate
Tanshinone
Trehalose
Triacetyluridine
Tumerone
ubiquinol
Uncaria
Urolithin A
velvet bean
vitamin D
vitamin D3
Vitexin
Withanolides
Wogonin
Xanthine
Xanthohumol
Xanthone
β-nicotinamide mononucleotide (NMN)
Other health conditions supported by velvet bean
AnxietyAnxiety Disorders
Depression
Diabetes
Energy (lack of)
Fatigue
Memory and Brain Function
Parkinson's Disease
Sex Drive (low)
Stress
Products containing velvet bean
Designs For Health
DopaBoost™
Pure Encapsulations
DopaPlus
Douglas Laboratories
TestoGain™
Douglas Laboratories
TestoGain™
