Relationship: Peripheral Neuropathy and DHA (docosahexaeonic acid)

Evidence supporting the use of: DHA (docosahexaeonic acid)
For the health condition: Peripheral Neuropathy

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis
Other ingredients for this health condition
Other health conditions supported by this ingredient
Products containing this ingredient

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

DHA (docosahexaenoic acid) is an omega-3 fatty acid primarily known for its roles in brain and eye health. Its use in supporting or treating peripheral neuropathy is based on emerging, but still limited, scientific evidence. Preclinical studies, particularly in animal models, have demonstrated that DHA may exert neuroprotective effects, reduce inflammation, and promote nerve regeneration. For instance, some rodent studies have shown that DHA supplementation can reduce neuropathic pain behaviors and improve nerve conduction following nerve injury. The proposed mechanisms include modulation of inflammatory pathways, enhancement of neuronal membrane fluidity, and support of remyelination processes.

However, clinical evidence in humans is sparse. Small pilot studies and observational data suggest some potential benefit of omega-3 supplementation (including DHA) in reducing neuropathic symptoms, especially in conditions like diabetic neuropathy, but the studies are often underpowered and combine DHA with EPA (another omega-3), making it difficult to isolate DHA's specific effects. No large-scale, well-controlled clinical trials have conclusively demonstrated that DHA alone is effective for peripheral neuropathy. As such, the current scientific evidence supports a possible, but not definitive, role for DHA in this context, and major clinical guidelines do not currently recommend DHA as a standard treatment for peripheral neuropathy. Further research is needed to establish its efficacy, optimal dosing, and safety for this indication.

More about DHA (docosahexaeonic acid)
More about Peripheral Neuropathy

Products containing DHA (docosahexaeonic acid)

Health Concerns

Brands

Evidence supporting the use of: DHA (docosahexaeonic acid)
For the health condition: Peripheral Neuropathy

Table of Contents

Synopsis

Other ingredients used for Peripheral Neuropathy

Other health conditions supported by DHA (docosahexaeonic acid)

Products containing DHA (docosahexaeonic acid)

Health Concerns

Brands

Evidence supporting the use of: DHA (docosahexaeonic acid)For the health condition: Peripheral Neuropathy

Table of Contents

Synopsis

Other ingredients used for Peripheral Neuropathy

Other health conditions supported by DHA (docosahexaeonic acid)

Products containing DHA (docosahexaeonic acid)

Evidence supporting the use of: DHA (docosahexaeonic acid)
For the health condition: Peripheral Neuropathy