Evidence supporting the use of: Vitamin B1 (thiamine HCl)
For the health condition: Peripheral Neuropathy

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B1 (thiamine HCl) is scientifically used to support or treat certain forms of peripheral neuropathy, particularly those related to thiamine deficiency. Thiamine is essential for nerve function and glucose metabolism. Deficiency in thiamine can lead to beriberi, which often presents with peripheral neuropathy as a prominent symptom. Clinical studies and historical case series have demonstrated that supplementation with thiamine can reverse neuropathic symptoms in patients with deficiency-related neuropathy. This is most relevant in conditions like chronic alcoholism, malnutrition, or malabsorptive disorders where thiamine deficiency is common.

However, the evidence for thiamine supplementation in peripheral neuropathy unrelated to deficiency (such as diabetic neuropathy) is less robust. Some small studies and clinical observations suggest potential benefits, but large, high-quality randomized trials are lacking. Modified forms of thiamine (e.g., benfotiamine) have shown some promise in diabetic neuropathy, but the standard thiamine HCl form has more limited evidence outside deficiency states.

In summary, there is clear scientific justification for using thiamine to treat peripheral neuropathy caused by its deficiency, but its broader use for other neuropathies is less well supported by current evidence.

More about Vitamin B1 (thiamine HCl)
More about Peripheral Neuropathy

Other health conditions supported by Vitamin B1 (thiamine HCl)

Alcoholism
Diabetes
Fatigue
Heart (weakness)
Memory and Brain Function
Peripheral Neuropathy

Products containing Vitamin B1 (thiamine HCl)

We currently have no products on Vitabase that contain this ingredient.