Evidence supporting the use of: Bifidobacterium animalis
For the body system: Peyer’s patches

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium animalis is a probiotic bacterium commonly found in the human gut and fermented dairy products. Its use in supporting the immune system, particularly through effects on Peyer’s patches (specialized lymphoid tissue in the small intestine involved in immune surveillance), is supported by emerging scientific evidence, though not yet fully established or definitive.

Several preclinical studies (mainly in animal models) have demonstrated that supplementation with B. animalis can enhance gut mucosal immunity. It has been observed to increase the number and activity of immune cells in Peyer’s patches, such as dendritic cells and lymphocytes, and to promote the production of secretory IgA, a key antibody in mucosal defense (reference). Some mechanistic studies suggest that B. animalis interacts with the gut epithelium and immune cells, influencing the maturation and function of Peyer’s patches and possibly improving the host’s resistance to intestinal pathogens.

However, direct clinical evidence in humans is limited, with most research focusing on general gut and immune health rather than explicitly on Peyer’s patches. The scientific rationale is plausible, and there is supporting data from animal and in vitro studies, but more robust, targeted human trials are needed to confirm these effects. Therefore, the use of B. animalis for supporting the Peyer’s patches body system is justified by preliminary scientific evidence, earning it a rating of 3 out of 5.

More about Bifidobacterium animalis
More about Peyer’s patches

Products containing Bifidobacterium animalis

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