Evidence supporting the use of: Rutosides
For the health condition: Phlebitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rutosides (also known as rutin or rutoside) are a group of flavonoids commonly found in certain plants and are used in some countries as venoactive drugs. Their use in supporting or treating phlebitis (inflammation of a vein) is primarily supported by scientific rationale and some clinical studies, though evidence is considered moderate in strength.

Rutosides are thought to exert their effect by increasing capillary resistance, reducing capillary permeability, and having anti-inflammatory and antioxidant properties. They are included in the class of drugs known as phlebotonics, which are used to treat chronic venous insufficiency (CVI) and related conditions such as varicose veins and sometimes phlebitis.

Some randomized, controlled trials and reviews (for example, Cochrane reviews and European Medicines Agency monographs) have reported that rutosides may help reduce symptoms such as swelling, pain, and heaviness in patients with venous disorders. However, most of the research focuses on chronic venous insufficiency rather than acute phlebitis specifically. Nevertheless, the anti-inflammatory and vascular-protective actions provide a mechanistic rationale for their use in phlebitis, and they are sometimes recommended or prescribed for this indication, especially in Europe.

Overall, while rutosides are not universally endorsed by all guidelines and the evidence is not robust for phlebitis per se, their use is supported by moderate-quality scientific evidence, particularly for related venous disorders, and is considered rational in the context of vein inflammation.

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Products containing Rutosides

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