Evidence supporting the use of: Eleutheroside
For the body system: Pituitary

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Table of Contents

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Eleutheroside is a group of active compounds found in Eleutherococcus senticosus, commonly known as Siberian ginseng. Traditionally, Siberian ginseng has been used in Eastern herbal medicine as an adaptogen—a substance believed to help the body cope with physical and mental stress and to support overall vitality, including the endocrine system. While the pituitary gland (or pituitary body) is central to hormone regulation, including stress response, there is no direct traditional reference to Eleutheroside or Siberian ginseng being used specifically to "support the pituitary body system" in isolation. Instead, traditional use more broadly encompasses support for energy, stamina, and resilience, which can indirectly relate to pituitary-adrenal functions. Scientific research has investigated Eleutherosides for their adaptogenic activities and potential effects on the hypothalamic-pituitary-adrenal (HPA) axis, but robust clinical evidence specifically demonstrating direct pituitary gland support is lacking. Current studies are mostly preclinical or involve small human trials, and do not provide strong, targeted evidence for pituitary support. Therefore, the justification for using Eleutheroside for the pituitary body system primarily stems from tradition rather than solid scientific validation, and the overall quality of evidence remains low to moderate.

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