Evidence supporting the use of: Vitex (unspecified)
For the body system: Pituitary

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Table of Contents

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitex (commonly referring to Vitex agnus-castus, or chaste tree) has a long-standing traditional use for supporting hormonal balance, particularly in relation to female reproductive health. The traditional rationale for its use ties into its reputed effects on the pituitary gland, sometimes called the "master gland" of the endocrine system. Historical herbal texts and folk practices suggest that Vitex was used to address menstrual irregularities, premenstrual syndrome (PMS), and certain symptoms associated with menopause. These uses are based on the belief that compounds in Vitex can influence the secretion of hormones such as prolactin by acting on the pituitary gland.

However, while there are some modern studies suggesting Vitex may have effects on the menstrual cycle and PMS symptoms—possibly via dopaminergic effects on prolactin secretion—direct, robust evidence of Vitex specifically supporting the pituitary gland as a whole is lacking. Most clinical trials and research focus on reproductive outcomes rather than pituitary health directly. Thus, while the traditional use of Vitex for "pituitary support" is established in herbal medicine, scientific validation specifically regarding pituitary function is limited, and the connection is largely inferred from its broader hormonal actions. The evidence rating reflects this gap between traditional application and scientific substantiation for this specific indication.

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