Evidence supporting the use of: Bupleurum falcatum
For the health condition: PMS (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bupleurum falcatum is primarily used in Traditional Chinese Medicine (TCM) for a variety of liver-related and gynecological conditions, including premenstrual syndrome (PMS). Its use for PMS is rooted in the traditional concept of "soothing liver qi" and regulating menstruation, which is thought to help alleviate the emotional and physical symptoms often experienced in PMS, such as irritability, breast tenderness, and mood swings. Historically, Bupleurum is a key ingredient in several classic herbal formulas like Xiao Yao San (Free and Easy Wanderer), which is commonly prescribed for PMS symptoms in East Asia.

Scientific evidence for Bupleurum falcatum's efficacy for PMS is limited and mostly indirect. While some studies have explored the anti-inflammatory, hepatoprotective, and mild adaptogenic effects of Bupleurum's active compounds (notably saikosaponins), there is a lack of high-quality, large-scale clinical trials specifically evaluating its use for PMS in humans. Some small studies and case series suggest potential benefit when used as part of multi-herb formulas, but these do not isolate Bupleurum’s effects. Consequently, its use for PMS is justified primarily by traditional practice and clinical experience rather than robust scientific validation. More research is needed to clarify its mechanisms and efficacy for this specific condition.

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Products containing bupleurum falcatum

Douglas Laboratories AdrenoMend™