Evidence supporting the use of: Flax lignans
For the health condition: PMS (general)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Flax lignans have traditionally been used in some cultures as part of dietary strategies to support women's hormonal health, including premenstrual syndrome (PMS). Lignans are phytoestrogens—plant-derived compounds with weak estrogenic activity—and flaxseed is one of the richest dietary sources. The rationale for their use in PMS is based on their potential to modulate estrogen metabolism and balance hormone levels, which may affect PMS symptoms that are thought to be related to hormonal fluctuations.

However, scientific validation for flax lignans specifically in the treatment or management of PMS is limited. A small number of studies have explored the effects of flaxseed supplementation on menstrual cycles and hormonal profiles, with some reporting minor improvements in cycle regularity and hormone ratios. Nevertheless, direct, high-quality clinical trials investigating flax lignans for PMS symptoms are lacking. Most evidence is extrapolated from broader research on phytoestrogens and hormonal balance rather than robust, condition-specific trials.

In summary, while the traditional use of flax lignans for PMS exists, and there is a plausible biological mechanism based on their phytoestrogen content, the clinical evidence to support their efficacy for PMS is weak and inconclusive. More research is needed to determine if flax lignans offer significant and reliable benefits for PMS.

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Products containing Flax lignans

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