Evidence supporting the use of: Chastetree
For the health condition: PMS Type D
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Chastetree (Vitex agnus-castus), also known as vitex, is commonly used to support premenstrual syndrome (PMS), including PMS Type D, which is characterized by depressive symptoms such as mood swings, irritability, and low mood. The use of Chastetree for PMS is supported by several clinical studies and systematic reviews. Research suggests that Chastetree works primarily by modulating prolactin levels through dopaminergic activity, which can help alleviate symptoms such as irritability, mood disturbances, and breast tenderness associated with PMS. A 2017 Cochrane review concluded that Vitex agnus-castus may be more effective than placebo for global PMS symptoms, although the quality of evidence was considered moderate and more high-quality studies are needed. Several randomized controlled trials have shown reductions in PMS symptoms, including depression and mood swings, although the effects are generally modest.
Historically, Chastetree has been used for centuries in traditional European herbal medicine for menstrual disorders, but its modern use is increasingly supported by scientific investigation. While the exact mechanisms are not fully understood, the evidence suggests that Chastetree may be helpful for mild to moderate PMS, including depressive symptoms (Type D), but it should not be considered a replacement for standard psychiatric care for severe mood disorders. Overall, the scientific support is moderate (rated 3/5), with more robust research needed for definitive conclusions.
Other health conditions supported by Chastetree
AmenorrheaDysmenorrhea
Fibroids (uterine)
Menopause
Menstrual Irregularity
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Sex Drive (low)