Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Boneset (Eupatorium perfoliatum) has a long history of traditional use in North American herbal medicine, particularly among Native Americans and later by European settlers. It was commonly used to treat “breakbone fever” (now known as dengue) and fevers associated with influenza and respiratory infections, including pneumonia. The herb was typically prepared as a tea or infusion and valued for its purported diaphoretic (promoting sweating) and immune-supporting properties, which were believed to help “break” fevers and support recovery from respiratory illnesses.

However, scientific evidence supporting boneset’s efficacy for pneumonia is minimal. Most contemporary research has focused on its general anti-inflammatory, immunomodulatory, or antiviral effects in vitro or in animal models, with very limited human data. No robust clinical trials have demonstrated its benefit specifically for pneumonia. As such, boneset’s use for pneumonia is primarily justified by tradition rather than modern scientific validation. Safety concerns also exist, as some Eupatorium species contain hepatotoxic pyrrolizidine alkaloids, although E. perfoliatum is generally considered less toxic.

In summary, boneset’s use in pneumonia is rooted in traditional herbal practices rather than high-quality scientific evidence. It should not be considered a substitute for standard medical therapy for pneumonia, and caution is advised due to potential toxicity and lack of proven efficacy.

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