Premna, particularly Premna serratifolia (commonly known as "Agnimantha" in Ayurveda), has a long tradition of use in various Asian medical systems, especially Ayurveda and Siddha. In these systems, Premna is considered one of the "Dashamoola" (ten roots) used in numerous classical formulations for treating fevers, inflammation, and respiratory ailments, including symptoms that may be associated with pneumonia such as cough, difficulty breathing, and chest congestion.

Historical Ayurvedic texts describe the use of Premna in decoctions and polyherbal preparations aimed at balancing doshas and alleviating respiratory distress. However, modern scientific validation of Premna’s efficacy specifically for pneumonia is lacking. Some in vitro and animal studies suggest anti-inflammatory, immunomodulatory, and antimicrobial properties, but these are not directly tied to pneumonia treatment in clinical settings. There are no robust randomized controlled trials or clinical studies specifically supporting its use for pneumonia in humans.

In summary, the use of Premna for pneumonia is primarily based on traditional practice and historical usage within herbal medicine systems, with limited scientific evidence supporting this specific indication.