Evidence supporting the use of: Activated charcoal
For the health condition: Poisoning (food)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Activated charcoal is scientifically validated for use in certain cases of poisoning, particularly in acute oral poisoning. Its effectiveness stems from its large surface area and porous structure, which allow it to adsorb a wide range of toxins and prevent their absorption from the gastrointestinal tract into the bloodstream. Clinical studies and toxicological guidelines support its use when administered within an hour of ingesting a toxic substance, especially if the substance is known to bind to charcoal (such as many drugs and plant toxins). Activated charcoal is less effective or ineffective for certain substances such as alcohols, heavy metals, and corrosives (acids or alkalis), as these do not bind well to its surface. Medical guidelines, including those from the American Academy of Clinical Toxicology, recommend activated charcoal as a first-line intervention in select poisoning cases, provided there are no contraindications (such as risk of aspiration or an unprotected airway). It is important to note that the use of activated charcoal is not a universal remedy for all types of poisoning and should be used under medical supervision. The evidence for its efficacy is strongest for early administration and specific toxins, while its benefit diminishes with delayed use or for substances poorly adsorbed by charcoal. Overall, the use of activated charcoal in poisoning is supported by a solid body of clinical research, though it is not universally applicable in all types of poisoning incidents.

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