Evidence supporting the use of: Dimercaptosuccinic acid (DMSA)
For the health condition: Poisoning (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Dimercaptosuccinic acid (DMSA) is scientifically validated for use in the treatment of poisoning, specifically heavy metal poisoning. DMSA is an orally administered chelating agent that binds to toxic metals such as lead, mercury, and arsenic, forming stable, water-soluble complexes that are excreted via the urine. Its clinical efficacy has been demonstrated in numerous studies and is endorsed by major health authorities, including the U.S. Food and Drug Administration (FDA), for the treatment of lead poisoning in children and adults. DMSA is considered safer and less toxic than older chelators like British Anti-Lewisite (BAL) and Ethylenediaminetetraacetic acid (EDTA), making it preferable in many clinical situations.

Randomized controlled trials and case series have shown that DMSA effectively lowers blood lead levels and improves symptoms of lead toxicity. It is also used off-label for poisoning with other metals, such as arsenic and mercury, although supporting evidence is strongest for lead. The World Health Organization and the Centers for Disease Control and Prevention include DMSA in their guidelines for the management of heavy metal poisoning. There is no evidence for its use in poisoning by non-metal substances. Overall, DMSA’s use for heavy metal poisoning is based on robust scientific evidence, regulatory approval, and well-established clinical protocols.

More about Dimercaptosuccinic acid (DMSA)
More about Poisoning (general)

Other health conditions supported by Dimercaptosuccinic acid (DMSA)

Chemical Poisoning
Heavy Metal Poisoning
Lead Poisoning
Mercury Poisoning
Poisoning (general)

Products containing Dimercaptosuccinic acid (DMSA)

We currently have no products on Vitabase that contain this ingredient.