Evidence supporting the use of: Blue cohosh
For the health condition: Pregnancy (herbs and supplements for)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Blue Cohosh (Caulophyllum thalictroides) has been used traditionally by Native American and early European settlers as an herbal remedy to support pregnancy and childbirth, particularly to induce labor and ease delivery. The root and rhizome of Blue Cohosh were often prepared as teas or tinctures and administered in the final weeks of pregnancy or during labor to purportedly stimulate uterine contractions. Despite this historical use, there is a lack of robust scientific evidence to validate its efficacy or safety for this purpose. Modern studies have raised significant concerns about potential toxicity, as Blue Cohosh contains alkaloids and glycosides (such as methylcytisine and caulosaponin) that can cause adverse cardiovascular effects in both mothers and infants, including reports of neonatal heart failure and stroke. Major medical and obstetric organizations advise against the use of Blue Cohosh during pregnancy due to these risks and the absence of demonstrated benefit in controlled clinical trials. In summary, while the use of Blue Cohosh for pregnancy support is grounded in traditional herbal practices, scientific research does not support its safety or effectiveness, and it is generally considered unsafe for pregnant women.

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